Modular synthesis of thiazoline and thiazole derivatives by using a cascade protocol

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Modular synthesis of thiazoline and thiazole derivatives by using a cascade protocol† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7ra05993k

Thiazolines and thiazoles are an integral part of numerous natural products, a number of drugs, and many useful molecules such as ligands for metal catalysis. We report the first common synthetic protocol for the synthesis of thiazoles and thiazolines. Novel molecules are efficiently synthesized by using readily available and inexpensive substrates. The reaction conditions are mild and pure pro...

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Synthesis and biological activities of new substituted thiazoline-quinoline derivatives.

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Dowex-50W-hyodrgen ion exchange resin was used as a reusable catalyst for the synthesis of oxazoline, imidazoline and thiazoline derivatives through condensation reaction between arylnitriles and 2-aminoalcohol, ethylenediamine or 2-aminoethanthiol. This process provides several advantages such as excellent yields of the products, simple operation, convenient separation and inexpensive and recy...

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ژورنال

عنوان ژورنال: RSC Advances

سال: 2017

ISSN: 2046-2069

DOI: 10.1039/c7ra05993k